7-hydroxymitragynine Products, 7-hydro, or 70h have become widely discussed within the kratom community. These concentrated forms are often marketed as tablets, shots, or supplements that deliver potent effects in small doses.
Although 7-hydroxymitragynine occurs naturally in the kratom plant, high-concentration products are not equivalent to traditional kratom leaf or balanced blends like those combining kratom and kava.
As regulations evolve across the United States, safety is more important than ever. Here is essential information for consumers about the current landscape, including where products are restricted, and best practices for using 7-hydro products from reputable suppliers, such as Real Botanicals.
The Regulatory Landscape: Why Rules Are Tightening
Federal Warnings and Scheduling Moves
The U.S. Food and Drug Administration has made clear that most products containing 7-hydroxymitragynine are being marketed illegally when sold as dietary supplements, foods, or therapeutic products.
The agency has issued multiple warning letters to companies selling concentrated 7-hydroxymitragynine products because these products are not approved for any medical or nutritional use and do not meet safety standards.
In mid-2025, the FDA recommended that 7-OH products be controlled under the Controlled Substances Act due to concerns about opioid-like effects and potential misuse.
Local Action in Los Angeles County
Los Angeles County has taken a particularly firm stance. Public health officials have issued notices that retailers must remove kratom and 7-hydroxymitragynine products immediately from shelves. Failure to comply can result in confiscation, fines, or other penalties.
These actions stem from reports of multiple fatal overdoses in the region linked to kratom and high-concentration 7-hydroxymitragynine products.
County health departments in California state that kratom and 7-OH products are not lawfully marketed as food, drugs, or dietary supplements in the U.S., and they remain classified as adulterants under current standards.
What These Regulations Mean for Consumers
Right now, the federal government hasn’t banned all kratom products. But regulators are focused on highly concentrated 7-OH compounds because of their opioid-like strength. Traditional kratom leaf and balanced formulations are treated differently from isolated or synthetic 7-hydroxymitragynine extracts. It’s essential to stay up to date, as enforcement varies by state and county.
Understanding 7-Hydroxymitragynine and Its Potency
7-hydroxymitragynine is one of the minor alkaloids found naturally in the kratom plant. In its natural context, it’s present at very low levels alongside many other compounds that together shape the overall effect of kratom. When isolated or concentrated to higher levels, 7-OH interacts with opioid receptors more strongly than the main kratom alkaloid, mitragynine.
Traditional kratom use, including products that combine kratom and kava for a smoother experience, tends to be better tolerated because the dose and matrix of alkaloids stay closer to what the plant naturally offers.
Summary of How To Use 7-Hydro Products Safely
| Safety Topic | Recommendation |
| Legal Check | Confirm local regulations before purchase and use |
| Product Source | Only use products with third-party lab testing from trusted brands (e.g., Real Botanicals) |
| Starting Dose | Begin with the lowest effective dose and wait to assess effects |
| Mixing Substances | Avoid alcohol and medications that depress the nervous system |
| Monitoring | Track effects and stop use if adverse reactions occur |
| Health Conditions | Consult a healthcare provider if you have existing conditions |
| Children and Minors | Never use kratom or 7-hydroxymitragynine products for minors |
How to Use 7-Hydro Products Safely
If you choose to use 7-hydro products like 7-hydro tablets or 7-hydro shots from reputable brands such as Real Botanicals, follow these steps to lower your risk and improve predictability:
1. Confirm Legal Status Where You Live
Before purchasing any product containing 7-hydroxymitragynine, be aware of your local regulations regarding its use. In places such as Los Angeles County, authorities are actively removing these products from retail stores and enforcing penalties for non-compliance.
Even where products are still legally sold, new regulations may restrict sales, labeling, packaging, or marketing claims.
2. Choose Reputable Brands With Lab Testing
Products from established companies, such as Real Botanicals, typically include third-party lab results. These results verify actual alkaloid levels and screen for contaminants. Certified lab testing increases transparency so you aren’t guessing what you’re dosing.
Always request a Certificate of Analysis (CoA) to confirm content and purity.
3. Start With Very Low Doses
7-hydroxymitragynine products are potent. A safe approach is to use the minimum effective dose and wait long enough to feel the effect before considering a higher dose.
Because potency can vary widely, even among products from the same supplier, err on the side of caution.
4. Avoid Mixing With Alcohol or Other Substances
The FDA and public health officials have warned that combining 7-hydroxymitragynine with alcohol, prescription medications, or recreational drugs increases the risk of serious side effects like respiratory depression.
5. Monitor Your Body and Stop If You Notice Adverse Effects
Common issues with high-potency alkaloids include nausea, dizziness, slowed breathing, and mood changes. If you notice concerning symptoms, stop use and consult a healthcare professional.
6. Understand Interactions With Other Supplements
7-hydroxymitragynine, kratom, and kava all affect the nervous system. Stacking them with other central nervous system depressants or stimulants can create unpredictable effects. Use caution and spacing between different products.
7. Seek Medical Advice If You Have a Health Condition
People with liver, kidney, cardiovascular, or respiratory conditions should consult a medical provider before using potent alkaloid products. A professional can provide guidance based on your medical history and medications.
Should I Use 7-Hydroxymitragynine Products
Using 7-hydroxymitragynine products safely means knowing both your product and the regulatory climate around it. Potent alkaloid products are not the same as traditional kratom leaf, and regulators are paying close attention to where misuse has led to harm.
By choosing tested products from vetted suppliers like Real Botanicals, staying informed about local regulations such as those in Los Angeles County, and following careful dosing guidelines, you can minimize risk and make informed decisions that protect your health.